{"title":"Flea \u0026 Tick Control","description":null,"products":[{"product_id":"seresto-flea-and-tick-collar-large-dog","title":"Seresto Flea and Tick Collar | Large Dog","description":"\u003cp\u003e - INGREDIENTS:Active Ingredients: Flumethrin 4.5%, Imidacloprid 10.0% - HEIGHT(INCHES): 1.500 - WIDTH(INCHES):4.750 - LENGTH(INCHES):4.750\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"Default Title","offer_id":42690315518014,"sku":"E8AH","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/e8ah-studio-0.jpg?v=1775839694"},{"product_id":"seresto-flea-and-tick-collar-small-dogs","title":"Seresto Flea and Tick Collar, Small Dogs","description":"\u003cp\u003e - INGREDIENTS:Active Ingredients: Flumethrin 4.5%, Imidacloprid 10.0% - HEIGHT(INCHES): 1.500 - WIDTH(INCHES):4.750 - LENGTH(INCHES):4.750\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"Default Title","offer_id":42690371256382,"sku":"E8AG","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/e8ag-studio-0.jpg?v=1775840671"},{"product_id":"rx-nexgard-combo-topical-for-cats-5-6-16-5lbs-single","title":"Rx Nexgard Combo Topical for Cats, 5.6-16.5lbs, Single","description":"\u003cp\u003eNexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) for Cats kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard (afoxolaner) and HEARTGARD Plus (ivermectin\/pyrantel).    All cats need parasite protection, even indoor cats. Applied monthly, NexGard COMBO is designed to deliver parasite protection to your cat year-round with an easy-to-use applicator. And it’s the first and only broad-spectrum solution that treats and kills tapeworms. NexGard COMBO topical solution is one-and-done monthly protection formulated specifically for cats. It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. - CAUTIONS\/WARNINGS:Store at 59-86F (15-30 C). Brief periods up to 104F (40C) are permitted. Protect from light. - DIRECTIONS:NexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is applied with an easy-to-use applicator that helps reduce stress and mess for cats and their owners. Apply once a month. - INGREDIENTS:Esafoxolaner - 12mg\/ml, Eprinomectin - 4mg\/ml, Praziquantel - 83mg\/ml - STORAGE\/DISPOSAL REQ:Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light. - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861133886,"sku":"012BI-160069","price":38.69,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012BI-160069-MAIN.jpg?v=1777394354"},{"product_id":"rx-nexgard-combo-topical-for-cats-1-8-5-5lbs-6pk","title":"Rx Nexgard Combo Topical for Cats, 1.8-5.5lbs, 6pk","description":"\u003cp\u003eNexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) for Cats kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard (afoxolaner) and HEARTGARD Plus (ivermectin\/pyrantel).    All cats need parasite protection, even indoor cats. Applied monthly, NexGard COMBO is designed to deliver parasite protection to your cat year-round with an easy-to-use applicator. And it’s the first and only broad-spectrum solution that treats and kills tapeworms. NexGard COMBO topical solution is one-and-done monthly protection formulated specifically for cats. It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. - CAUTIONS\/WARNINGS:Store at 59-86F (15-30 C). Brief periods up to 104F (40C) are permitted. Protect from light. - DIRECTIONS:NexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is applied with an easy-to-use applicator that helps reduce stress and mess for cats and their owners. Apply once a month. - INGREDIENTS:Esafoxolaner - 12mg\/ml, Eprinomectin - 4mg\/ml, Praziquantel - 83mg\/ml - STORAGE\/DISPOSAL REQ:Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light. - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861166654,"sku":"012BI-160021","price":157.69,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012BI-160021-MAIN.jpg?v=1777394359"},{"product_id":"rx-nexgard-combo-topical-for-cats-1-8-5-5lbs-3pk","title":"Rx Nexgard Combo Topical for Cats, 1.8-5.5lbs, 3pk","description":"\u003cp\u003eNexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) for Cats kills fleas and ticks, prevents heartworm disease, and treats and controls hookworms, roundworms and tapeworms. NexGard COMBO topical solution is parasite protection for cats from the maker of vet-recommended NexGard (afoxolaner) and HEARTGARD Plus (ivermectin\/pyrantel).    All cats need parasite protection, even indoor cats. Applied monthly, NexGard COMBO is designed to deliver parasite protection to your cat year-round with an easy-to-use applicator. And it’s the first and only broad-spectrum solution that treats and kills tapeworms. NexGard COMBO topical solution is one-and-done monthly protection formulated specifically for cats. It is safe and approved for cats and kittens as young as 8 weeks old, weighing 1.8 pounds or more. - CAUTIONS\/WARNINGS:Store at 59-86F (15-30 C). Brief periods up to 104F (40C) are permitted. Protect from light. - DIRECTIONS:NexGard COMBO (esafoxolaner, eprinomectin, and praziquantel topical solution) is applied with an easy-to-use applicator that helps reduce stress and mess for cats and their owners. Apply once a month. - INGREDIENTS:Esafoxolaner - 12mg\/ml, Eprinomectin - 4mg\/ml, Praziquantel - 83mg\/ml - STORAGE\/DISPOSAL REQ:Store at 59°–86°F (15°–30° C). Brief periods up to 104°F (40°C) are permitted. Protect from light. - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861232190,"sku":"012BI-160009","price":81.99,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012BI-160009-MAIN.jpg?v=1777394363"},{"product_id":"rx-nexgard-dog-60-1-121lb-x-6-tablets","title":"Rx NexGard Dog 60.1-121lb x 6 tablets","description":"\u003cp\u003eNexGard Chewables A convenient solution to an annoying problem--NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.  Compare the competition and see which flea and tick killer meets your expections.       On dogs   Kills fleas*    Kills ticks  Soft chew*  Dogs prefer\u0026amp;#177;     NexGard(afoxolaner)   \u0026amp;#x2713;    \u0026amp;#x2713;  \u0026amp;#x2713;  \u0026amp;#x2713;     COMFORTIS(spinosad)   \u0026amp;#x2713;    X  X  X     TRIFEXIS(spinosad + milbemycin ocime)   \u0026amp;#x2713;    X  X  NA   *Comparison of external parasites. These comparisons are based on label information. \u0026amp;#177;Data on file at Merial.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861297726,"sku":"012MER-72412","price":169.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72412-1-HR.jpg?v=1777394367"},{"product_id":"rx-nexgard-dogs-60-1-120-lbs-x-1-tablet","title":"Rx NexGard Dogs 60.1-120 lbs x 1 tablet","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861363262,"sku":"012MER-72411-SINGLE","price":39.39,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72411-SINGLE-MAIN.jpg?v=1777394373"},{"product_id":"rx-nexgard-dog-60-121-0lb-x-3-tablets","title":"Rx NexGard Dog 60-121.0lb x 3 tablets","description":"\u003cp\u003eNexGard Chewables A convenient solution to an annoying problem--NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.  Compare the competition and see which flea and tick killer meets your expections.       On dogs   Kills fleas*    Kills ticks  Soft chew*  Dogs prefer\u0026amp;#177;     NexGard(afoxolaner)   \u0026amp;#x2713;    \u0026amp;#x2713;  \u0026amp;#x2713;  \u0026amp;#x2713;     COMFORTIS(spinosad)   \u0026amp;#x2713;    X  X  X     TRIFEXIS(spinosad + milbemycin ocime)   \u0026amp;#x2713;    X  X  NA   *Comparison of external parasites. These comparisons are based on label information. \u0026amp;#177;Data on file at Merial.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730861396030,"sku":"012MER-72411","price":96.29,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72411-1-HR.jpg?v=1777394377"},{"product_id":"rx-nexgard-dog-24-1-60lb-x-1-tablet","title":"Rx NexGard Dog 24.1-60lb x 1 tablet","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881155134,"sku":"012MER-72410-TAB","price":38.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72410-TAB_Bottle-1-HR.jpg?v=1777395203"},{"product_id":"rx-nexgard-dog-24-1-60lb-x-6-tablets","title":"Rx NexGard Dog 24.1-60lb x 6 tablets","description":"\u003cp\u003eNexGard Chewables A convenient solution to an annoying problem--NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.  Compare the competition and see which flea and tick killer meets your expections.       On dogs   Kills fleas*    Kills ticks  Soft chew*  Dogs prefer\u0026amp;#177;     NexGard(afoxolaner)   \u0026amp;#x2713;    \u0026amp;#x2713;  \u0026amp;#x2713;  \u0026amp;#x2713;     COMFORTIS(spinosad)   \u0026amp;#x2713;    X  X  X     TRIFEXIS(spinosad + milbemycin ocime)   \u0026amp;#x2713;    X  X  NA   *Comparison of external parasites. These comparisons are based on label information. \u0026amp;#177;Data on file at Merial.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881220670,"sku":"012MER-72410","price":167.89,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72410-1-HR.jpg?v=1777395208"},{"product_id":"rx-nexgard-dog-24-60-0lb-x-3-tablets","title":"Rx NexGard Dog 24-60.0lb x 3 tablets","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881286206,"sku":"012MER-72409","price":95.39,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72409-1-HR.jpg?v=1777395213"},{"product_id":"rx-nexgard-dog-10-1-24lb-x-6-tablet","title":"Rx NexGard Dog 10.1-24lb x 6 tablet","description":"\u003cp\u003eNexGard Chewables A convenient solution to an annoying problem--NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.  Compare the competition and see which flea and tick killer meets your expections.       On dogs   Kills fleas*    Kills ticks  Soft chew*  Dogs prefer\u0026amp;#177;     NexGard(afoxolaner)   \u0026amp;#x2713;    \u0026amp;#x2713;  \u0026amp;#x2713;  \u0026amp;#x2713;     COMFORTIS(spinosad)   \u0026amp;#x2713;    X  X  X     TRIFEXIS(spinosad + milbemycin ocime)   \u0026amp;#x2713;    X  X  NA   *Comparison of external parasites. These comparisons are based on label information. \u0026amp;#177;Data on file at Merial.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881318974,"sku":"012MER-72408","price":164.39,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72408-1-HR.jpg?v=1777395217"},{"product_id":"rx-nexgard-dog-10-24lbs-x-1-tablet","title":"Rx NexGard Dog 10-24lbs x 1 tablet","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881384510,"sku":"012MER-72407-SINGLE","price":38.19,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72407-SINGLE_Bottle-1-HR.jpg?v=1777395221"},{"product_id":"rx-nexgard-dog-4-10lbs-x-1-tablet","title":"Rx NexGard Dog 4-10lbs x 1 tablet","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881417278,"sku":"012MER-72406-CHEW","price":37.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72406-CHEW_Bottle-1-HR.jpg?v=1777395226"},{"product_id":"rx-nexgard-dog-4-10lbs-x-6-tablets","title":"Rx NexGard Dog 4-10lbs x 6 tablets","description":"\u003cp\u003eNexGard Chewables, from PetScript Direct, are a convenient solution to an annoying problem—\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003eNEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that acts on the nervous systems of fleas and ticks, causing hyperexcitation and death, and provides protection for a full 30 days. NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by rapidly and safely absorbing into your pet's bloodstream and causes uncontrolled activity in the fleas' and ticks' central nervous systems, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication. Compare the competition and see which flea and tick killer meets your expectations. On dogs, Kills fleas* Kills ticks Soft chew* Dogs prefer± NexGard(afoxolaner) ✓ ✓ ✓ ✓ COMFORTIS(spinosad) ✓ X X X *Comparison of external parasites. These comparisons are based on label information. ±Data on file at Merial.\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e⚠️ Prescription items are NON-RETURNABLE and NON-REFUNDABLE.\u003c\/p\u003e\u003ch3\u003eSpecifications\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHeight:\u003c\/strong\u003e 4.000\"\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWidth:\u003c\/strong\u003e 1.000\"\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLength:\u003c\/strong\u003e 4.500\"\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"NexGard","offers":[{"title":"4-10lbs \/ (6-mo. supply)","offer_id":42730881482814,"sku":"012MER-72406","price":160.89,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72406-1-HR.jpg?v=1779213697"},{"product_id":"rx-nexgard-dog-4-10lbs-x-3-tablets","title":"Rx NexGard Dog 4-10lbs x 3 tablets","description":"\u003cp\u003eNexGard Chewables A convenient solution to an annoying problem--NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.  Compare the competition and see which flea and tick killer meets your expections.       On dogs   Kills fleas*    Kills ticks  Soft chew*  Dogs prefer\u0026amp;#177;     NexGard(afoxolaner)   \u0026amp;#x2713;    \u0026amp;#x2713;  \u0026amp;#x2713;  \u0026amp;#x2713;     COMFORTIS(spinosad)   \u0026amp;#x2713;    X  X  X     TRIFEXIS(spinosad + milbemycin ocime)   \u0026amp;#x2713;    X  X  NA   *Comparison of external parasites. These comparisons are based on label information. \u0026amp;#177;Data on file at Merial.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730881515582,"sku":"012MER-72405","price":91.39,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72405-1-HR.jpg?v=1777395235"},{"product_id":"nexgard-plus-chewables-for-dogs","title":"NexGard PLUS Chewables for Dogs","description":"\u003cp\u003eNexGard PLUS (afoxolaner, moxidectin, and pyrantel chewable tablets) provides comprehensive, one-and-done monthly parasite protection for your dog. This powerful formula protects your dog from fleas and ticks, while also preventing heartworm disease and treating roundworms and hookworms—all in a delicious, beef-flavored soft chew that makes administration a delight rather than a chore.\u003c\/p\u003e\n\n\u003cp\u003eSafe and approved for puppies as young as 8 weeks old, NexGard PLUS comes from the makers of the #1 veterinarian-recommended HEARTGARD Plus (ivermectin\/pyrantel) chews. These easy-to-give chews ensure your pet remains protected year-round against ever-present risks. It kills adult fleas fast, before they can lay eggs, and is approved to kill the four species of ticks most commonly found on dogs in the US.\u003c\/p\u003e\n\n\u003cp\u003eHeartworm disease is a serious, potentially deadly condition reported in all 50 states, affecting both indoor and outdoor pets. Because just one bite from an infected mosquito can put your pet at risk, the American Heartworm Society recommends year-round prevention. NexGard PLUS offers a convenient way to meet this professional standard of care while keeping your dog safe from intestinal parasites.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eImportant Safety Information:\u003c\/strong\u003e All dogs should be tested for heartworms prior to starting a preventive program. Use with caution in dogs with a history of seizures or neurological disorders.\u003c\/p\u003e\n\n\u003cul\u003e\n  \u003cli\u003e\n\u003cstrong\u003eDIRECTIONS:\u003c\/strong\u003e Give orally once a month.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eINGREDIENTS:\u003c\/strong\u003e Afoxolaner, Moxidectin, Pyrantel.\u003c\/li\u003e\n  \u003cli\u003e\n\u003cstrong\u003eSTORAGE\/DISPOSAL REQ:\u003c\/strong\u003e Store in original package at or below 25°C (77°F) with excursions permitted up to 40°C (104°F).\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"NexGard","offers":[{"title":"Single \/ 4.1-8 Lbs","offer_id":42730888855614,"sku":"012MER-123242-1","price":44.29,"currency_code":"USD","in_stock":true},{"title":"Single \/ 8.1-17 Lbs","offer_id":42730888888382,"sku":"012MER-168349-1","price":45.09,"currency_code":"USD","in_stock":true},{"title":"Single \/ 17.1-33 Lbs","offer_id":42730888921150,"sku":"012MER-168359-1","price":46.49,"currency_code":"USD","in_stock":true},{"title":"Single \/ 33.1-66 Lbs","offer_id":42730888953918,"sku":"012MER-168355-1","price":47.79,"currency_code":"USD","in_stock":true},{"title":"Single \/ 66.1-132 Lbs","offer_id":42730888986686,"sku":"012MER-168352-1","price":48.99,"currency_code":"USD","in_stock":true},{"title":"3pk \/ 4.1-8 Lbs","offer_id":42730889019454,"sku":"012MER-123242","price":113.49,"currency_code":"USD","in_stock":true},{"title":"3pk \/ 8.1-17 Lbs","offer_id":42730889052222,"sku":"012MER-168349","price":115.19,"currency_code":"USD","in_stock":true},{"title":"3pk \/ 17.1-33 Lbs","offer_id":42730889084990,"sku":"012MER-168359","price":122.89,"currency_code":"USD","in_stock":true},{"title":"3pk \/ 33.1-66 Lbs","offer_id":42730889117758,"sku":"012MER-168355","price":123.79,"currency_code":"USD","in_stock":true},{"title":"3pk \/ 66.1-132 Lbs","offer_id":42730889150526,"sku":"012MER-168352","price":130.79,"currency_code":"USD","in_stock":true},{"title":"6pk \/ 4.1-8 Lbs","offer_id":42730889183294,"sku":"012MER-123241","price":210.59,"currency_code":"USD","in_stock":true},{"title":"6pk \/ 8.1-17 Lbs","offer_id":42730889216062,"sku":"012MER-168350","price":214.19,"currency_code":"USD","in_stock":true},{"title":"6pk \/ 17.1-33 Lbs","offer_id":42730889248830,"sku":"012MER-168351","price":228.39,"currency_code":"USD","in_stock":true},{"title":"6pk \/ 33.1-66 Lbs","offer_id":42730889281598,"sku":"012MER-168357","price":235.59,"currency_code":"USD","in_stock":true},{"title":"6pk \/ 66.1-132 Lbs","offer_id":42730889314366,"sku":"012MER-168354","price":242.49,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-123241-MAIN.jpg?v=1777395293"},{"product_id":"rx-nexgard-dog-10-24lbs-x-3-tablets","title":"Rx NexGard Dog 10-24lbs x 3 tablets","description":"\u003cp\u003eNexGard Chewables  A convenient solution to an annoying problem—NEXGARD is the first flea and tick killer in a beef-flavored chew, a piece of health your dog will easily love. Designed specifically for dogs, NEXGARD kills adult fleas before they lay eggs, and kills ticks upon administration. Each chewable contains an ingredient, afoxolaner, that works on the nervous system of fleas and ticks which causes hyperexcitation and then death, and continues protection for a full 30 days.    NexGard contains a brand-new ingredient not used in any other flea and tick protection. Afoxolaner, the ingredient in NexGard, works by absorbing rapidly and safely into your pet's bloodstream and causes uncontrolled activity the flea's and tick's central nervous system, which causes death. Afoxolaner is slowly excreted through your pet's metabolism, which allows NexGard to continue to provide effective treatment for a full 30 days. This means amazing protection in a tasty morsel! NexGard can be taken alongside your regular heartworm medication. NexGard is a prescription-only medication.  Compare the competition and see which flea and tick killer meets your expections.            On dogs    Kills fleas*     Kills ticks   Soft chew*   Dogs prefer\u0026amp;#177;        NexGard(afoxolaner)    \u0026amp;#x2713;     \u0026amp;#x2713;   \u0026amp;#x2713;   \u0026amp;#x2713;        COMFORTIS(spinosad)    \u0026amp;#x2713;     X   X   X      *Comparison of external parasites. These comparisons are based on label information.  \u0026amp;#177;Data on file at Merial.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Cautions \u0026amp; Warnings  Caution: Federal (USA) law restricts this drug to use by or on the order of licensed veterinarian.  Contraindications: There are no known contraindications for the use of NEXGARD.  Warning: Not for use in humans. Keep this and all drugs out of the reach of children. In case of accidental ingestion, contact a physician immediately.  Precautions: The safe use of NEXGARD in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures. - DIRECTIONS:Dosage \u0026amp; Administration NEXGARD is given orally once a month, at the minimum dosage of 1.14 mg\/lb (2.5mg\/kg).  Dosing Schedule:     Body Weight   Afoxolaner per Chewable (mg)    Chewables Administered     4.0 to 10.0 lbs.   11.3    One     10.1 to 24.0 lbs.   28.3    One     24.1 to 60.0 lbs.   68    One     60.1 to 121.0 lbs.   136    One     Over 121.0 lbs.   Administer the appropriate combination of chewables    NEXGARD can be administered with or without food. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. If a dose is missed, administer NEXGARD and resume a monthly dosing schedule. Flea Treatment and Prevention: Treatment with NEXGARD may begin at any time of the year. In areas where fleas are common year-round, monthly treatment with NEXGARD should continue the entire year without interruption.  To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product.  Tick Treatment and Control: Treatment with NEXGARD may begin at any time of the year - INGREDIENTS:Ingredients Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg\/lb (2.5 mg\/kg). Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. - STORAGE\/DISPOSAL REQ:Store at 59-86 degrees F - HEIGHT(INCHES): 4.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):4.500\u003c\/p\u003e","brand":"NexGard","offers":[{"title":"Default Title","offer_id":42730896818238,"sku":"012MER-72407","price":93.29,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012MER-72407-1-HR.jpg?v=1777396209"},{"product_id":"rx-trifexis-60-1-120-lbs-brown-x-1-tablet","title":"Rx Trifexis 60.1-120 lbs (Brown) x 1 tablet","description":"\u003cp\u003eTrifexis (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies, according to their weight. Each chewable, flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg\/lb (30 mg\/kg) and a minimum milbemycin oxime dose of 0.2 mg\/lb (0.5 mg\/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.    Trifexis was formulated for the prevention of heartworm disease (Dirofilaria immitis) for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies eight weeks of age or older and five pounds of body weight or greater.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"60.1-120lbs (Brown)","offer_id":42739688177726,"sku":"012ELC-60-1-120-1","price":29.58,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-60-1-120-1_Bottle-1-HR.jpg?v=1777733013"},{"product_id":"rx-trifexis-60-1-120-lbs-brown-x-6-tablets","title":"Rx Trifexis 60.1-120 lbs (Brown) x 6 tablets","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"60.1-120 lbs (Brown)","offer_id":42739688210494,"sku":"012ELC-60-1-120","price":177.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-60-1-120-MAIN.jpg?v=1777733018"},{"product_id":"rx-trifexis-5-10-lbs-pink-x-1-tablet","title":"Rx Trifexis 5-10 lbs (Pink) x 1 tablet","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"5-10lbs (Pink)","offer_id":42739688243262,"sku":"012ELC-5-10-1","price":25.68,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-5-10-1_Bottle-1-HR.jpg?v=1777733022"},{"product_id":"rx-trifexis-5-10-lbs-pink-x-6-tablets","title":"Rx Trifexis 5-10 lbs (Pink) x 6 tablets","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"5-10 lbs (Pink)","offer_id":42739688276030,"sku":"012ELC-5-10","price":154.09,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-5-10-MAIN.jpg?v=1777733027"},{"product_id":"rx-trifexis-40-1-60-lbs-blue-x-1-tablet","title":"Rx Trifexis  40.1-60 lbs (Blue) x 1 tablet","description":"\u003cp\u003eTrifexis (spinosad and milbemycin oxime) is available in five sizes for oral administration to dogs and puppies, according to their weight. Each chewable, flavored tablet is formulated to provide a minimum spinosad dose of 13.5 mg\/lb (30 mg\/kg) and a minimum milbemycin oxime dose of 0.2 mg\/lb (0.5 mg\/kg). Spinosad is a member of the spinosyns class of insecticides, which are non-antibacterial tetracyclic macrolides. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions C41H65NO10 and C42H67NO10, respectively. Milbemycin oxime is a macrocyclic lactone anthelmintic, containing two major factors, A3 and A4 of milbemycin oxime. The approximate ratio of A3:A4 is 20:80. Milbemycin A4 5-oxime has the chemical composition of C32H45NO7 and milbemycin A3 5-oxime has the chemical composition of C31H43NO7.    Trifexis was formulated for the prevention of heartworm disease (Dirofilaria immitis) for the prevention and treatment of flea infestations (Ctenocephalides felis), and the treatment and control of adult hookworm (Ancylostoma caninum), adult roundworm (Toxocara canis and Toxascaris leonina) and adult whipworm (Trichuris vulpis) infections in dogs and puppies eight weeks of age or older and five pounds of body weight or greater.    Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"40.1-60lbs (Blue)","offer_id":42739688308798,"sku":"012ELC-40-1-60-1","price":29.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-40-1-60-1_Bottle-1-HR.jpg?v=1777733031"},{"product_id":"rx-trifexis-40-1-60-lbs-blue-x-6-tablet","title":"Rx Trifexis  40.1-60 lbs (Blue) x 6 tablet","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"40.1-60 lbs (Blue)","offer_id":42739688407102,"sku":"012ELC-40-1-60","price":174.59,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-40-1-60-MAIN.jpg?v=1777733035"},{"product_id":"rx-trifexis-20-1-40-lbs-green-x-1-tablet","title":"Rx Trifexis 20.1-40 lbs (Green) x 1 tablet","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"20.1-40lbs (Green)","offer_id":42739688439870,"sku":"012ELC-20-1-40-1","price":27.72,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-20-1-40-1_Bottle-1-HR.jpg?v=1777733039"},{"product_id":"rx-trifexis-20-1-40-lbs-green-x-6-tablet","title":"Rx Trifexis 20.1-40 lbs (Green) x 6 tablet","description":"\u003cp\u003eTrifexis  Trifexis monthly heartworm medication for dogs also kills fleas and controls adult hookworms, roundworms and whipworms. Chewable tablet safe for dogs and puppies 8 weeks of age or older and 5 lbs of body weight or more. Begins killing fleas within 30 minutes. Trifexis kills fleas before they can lay eggs.  Prescription items are NON-RETURNABLE and NON-REFUNDABLE. - CAUTIONS\/WARNINGS:Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.  Warnings: Not for human use. Keep this and all drugs out of the reach of children. Serious adverse reactions have been reported following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis (see ADVERSE REACTIONS). Precautions: Treatment with fewer than 3 monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention (see EFFECTIVENESS). Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Trifexis is not effective against adult D. immitis. While the number of circulating microfilariae may decrease following treatment, Trifexis is not indicated for microfilariae clearance (see ANIMAL SAFETY). Mild, transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some dogs treated with milbemycin oxime carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae. Use with caution in breeding females (see ANIMAL SAFETY). The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy (see ADVERSE REACTIONS). Puppies less than 14 weeks of age may experience a higher rate of vomiting (see ANIMAL SAFETY). Adverse Reactions: In a well-controlled US field study, which included a total of 352 dogs (176 treated with Trifexis and 176 treated with an active control), no serious adverse reactions were attributed to administration of Trifexis. All reactions were regarded as mild. Over the 180-day study period, all observations of potential adverse reactions were recorded. Reactions that occurred at an incidence \u0026amp;gt;1% (average monthly rate) within any of the 6 months of observation are presented in the following table. The most frequently reported adverse reaction in dogs in the Trifexis group was vomiting. Average Monthly Rate (%) of Dogs With Adverse Reactions                                         Adverse Reaction                                       Trifexis Chewable Tablets\u0026amp;ordf*                                       Active Control Tablets\u0026amp;ordf*                                                         Vomiting                                       6.13                                       3.08                                                         Pruritus                                       4.00                                       4.91                                                         Lethargy                                       2.63                                       1.54                                                         Diarrhea                                       2.25                                       1.54                                                         Dermatitis                                       1.47                                       1.45                                                         Skin Reddening                                       1.37                                       1.26                                                         Decreased appetite                                       1.27                                       1.35                                                         Pinnal Reddening                                       1.18                                       0.87                             \u0026amp;ordf*=176 dogs In the US field study, one dog administered Trifexis experienced a single mild seizure 2 1\/2 hours after receiving the second monthly dose. The dog remained enrolled and received four additional monthly doses after the event and completed the study without further incident. Following concomitant extra-label use of ivermectin with spinosad alone, a component of Trifexis, some dogs have experienced the following clinical signs: trembling\/twitching, salivation\/drooling, seizures, ataxia, mydriasis, blindness and disorientation. Spinosad alone has been shown to be safe when administered concurrently with heartworm preventatives at label directions. In US and European field studies, no dogs experienced seizures when dosed with spinosad alone at the therapeutic dose range of 13.5-27.3 mg\/lb (30-60 mg\/kg), including 4 dogs with pre-existing epilepsy. Four epileptic dogs that received higher than the maximum recommended dose of 27.3 mg\/lb (60 mg\/kg) experienced at least one seizure within the week following the second dose of spinosad, but no seizures following the first and third doses. The cause of the seizures observed in the field studies could not be determined. For technical assistance or to report a suspected adverse drug reaction, contact Elanco Animal Health at 1-888-545-5973. Additional information can be found at www.trifexis.com. Alternatively, suspected adverse drug reactions may be reported to FDA at 1-800-FDA-VETS or http:\/\/www.fda.gov\/AnimalVeterinary\/SafetyHealth\/ReportaProblem\/ucm055305.htm - DIRECTIONS:Dosage and Administration: Trifexis is given orally, once a month at the minimum dosage of 13.5 mg\/lb (30 mg\/kg) spinosad and 0.2 mg\/lb (0.5 mg\/kg) milbemycin oxime body weight. For heartworm prevention, give once monthly for at least 3 months after exposure to mosquitoes (see Effectivness). Dosage Schedule:                                         Body Weight                                       Spinosad Per Tablet (mg)                                       Milbemycin oxime Per Tablet (mg)                                       Tablets Administered                                                         5 to 10 lbs                                       140                                       2.3                                       One                                                         10.1 to 20 lbs                                       270                                       4.5                                       One                                                         20.1 to 40 lbs                                       560                                       9.3                                       One                                                         40.1 to 60 lbs                                       810                                       13.5                                       One                                                         60.1 to 120 lbs                                       1620                                       27                                       One                                                         Over 120 lbs                                       Administer the appropriate combination of tablets                             Administer Trifexis with food for maximum effectiveness. If a dose is missed and a monthly interval between doses is exceeded, then immediate administration of Trifexis with food and resumption of monthly dosing will minimize the opportunity for the development of adult heartworm infections and flea reinfestations. If vomiting occurs within an hour of administration, redose with another full dose. Heartworm Prevention: Trifexis should be administered at monthly intervals beginning within 1 month of the dog's first seasonal exposure and continuing until at least 3 months after the dog's last seasonal exposure to mosquitoes (see EFFECTIVENESS). Trifexis may be administered year round without interruption. When replacing another heartworm preventative product, the first dose of TRIFEXIS should be given within a month of the last dose of the former medication. Flea Treatment and Prevention: Treatment with Trifexis may begin at any time of the year, preferably starting one month before fleas become active and continuing monthly through the end of flea season. In areas where fleas are common year-round, monthly treatment with TRIFEXIS should continue the entire year without interruption. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea protection product. Intestinal Nematode Treatment and Control: Trifexis also provides treatment and control of roundworms (T. canis, T. leonina), hookworms (A. caninum) and whipworms (T. vulpis). Dogs may be exposed to and can become infected with roundworms, whipworms and hookworms throughout the year, regardless of season or climate. Clients should be advised of measures to be taken to prevent reinfection with intestinal parasites. Contraindications: There are no known contraindications to the use of Trifexis. - INGREDIENTS:How Supplied: Trifexis is available in five tablet sizes. Each tablet size is available in color-coded packages of 6 tablets. 5-10 lbs (140 mg spinosad and 2.3 mg milbemycin oxime) 10.1-20 lbs (270 mg spinosad and 4.5 mg milbemycin oxime) 20.1-40 lbs (560 mg spinosad and 9.3 mg milbemycin oxime) 40.1-60 lbs (810 mg spinosad and 13.5 mg milbemycin oxime) 60.1-120 lbs (1620 mg spinosad and 27 mg milbemycin oxime) - STORAGE\/DISPOSAL REQ:Store at 20-25C (68-77F)  excursions permitted between 15-30C (59-86F). - HEIGHT(INCHES): 1.000 - WIDTH(INCHES):1.000 - LENGTH(INCHES):1.000\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"20.1-40 lbs (Green)","offer_id":42739690864702,"sku":"012ELC-20-1-40","price":166.29,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/012ELC-20-1-40-MAIN.jpg?v=1777733044"},{"product_id":"seresto-flea-and-tick-control-for-cats","title":"Seresto Flea and Tick Control for Cats","description":"\u003cp\u003e - CAUTIONS\/WARNINGS:Keep the collar in the bag and in the outer packaging until use. As with any pesticide product  do not allow small children to play with the collar or reflectors  or to put them into their mouths. Avoid contact with eyes  skin or clothing. Wash thoroughly with soap and cold water after fitting the collar. People with sensitivity reactions to the ingredients of the collar should avoid contact with the collar. Choking hazard. Contains small parts. Do not place collar or reflectors in mouth. Not intended for use on humans. \u0026lt;br\u0026gt;\u003cbr\u003e\nFor external use on cats only. Do not use on other animals. Do not use on kittens under ten weeks of age. Do not get this product in cats eyes or mouth. As with any product  consult your veterinarian before using this product on debilitated  aged  breeding  pregnant  or nursing animals. Individual sensitivities  while rare  may occur after using ANY pesticide product for pets. If signs of sensitivity occur  remove collar and bathe your pet with mild soap and rinse with large amounts of water. If signs persist  or become more severe  consult a veterinarian immediately. If your animal is on medication  consult your veterinarian before using this or any other product.\u0026lt;br\u0026gt; - DIRECTIONS:DIRECTIONS FOR USE \u0026lt;br\u0026gt;\u003cbr\u003e\nIt is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not contaminate feed or food. \u0026lt;br\u0026gt;\u003cbr\u003e\nHOW TO APPLY \u0026lt;br\u0026gt;\u003cbr\u003e\nOne collar per animal to be fastened around the neck. Remove collar from protective bag directly before use. Unroll collar and make sure that there are no remnants from the plastic connectors inside the collar. Insert end of the collar through the buckle. Adjust the collar around the animals neck without tightening it too tight (as a guide  it should be possible to insert 2 fingers between the collar and the neck). Pull excess collar through the loop(s) and cut off any excess length extending 1 inch (2 cm) beyond the loop(s). \u0026lt;br\u0026gt;\u003cbr\u003e\nAfter application of the collar  three reflector clips may be fixed permanently to the collar to increase the animals visibility in the dark. Take the clips out of the bag. The clips should be evenly distributed on the non-overlapping part of the collar. The clips are correctly applied when a clicking sound is heard. For safety reasons once the reflectors are fixed to the collar the clasp closes permanently and cannot be re-opened. The collar should be worn continuously for the 8 month protection period. Check periodically and adjust fit if necessary  especially when kittens are rapidly growing. This collar is designed with a safety-closure mechanism. In the unlikely event of a cat being trapped  the cats own strength is sufficient to widen the collar to allow for quick release. \u0026lt;br\u0026gt;\u003cbr\u003e\nReplace the collar after 8 months for optimal tick and flea protection.\u0026lt;br\u0026gt;\u003cbr\u003e\n \u0026lt;br\u0026gt;\u003cbr\u003e\nPRODUCT INFORMATION \u0026lt;br\u0026gt;\u003cbr\u003e\nKills fleas which may cause flea allergy dermatitis (FAD) or flea bite hypersensitivity (FBH). \u0026lt;br\u0026gt;\u003cbr\u003e\nSeresto kills existing fleas on cats within 24 hours. Re-infesting fleas are killed within 2 hours with protection against further flea infestation lasting eight (8) months. Pre-existing pupae in the environment may continue to emerge for six (6) weeks or longer depending upon the climatic conditions. Seresto aids in control of flea larvae in the cats surroundings following contact with a Seresto-treated cat. \u0026lt;br\u0026gt;\u003cbr\u003e\nTicks already on the cat prior to treatment may not be killed immediately after collar application and may remain attached and visible. At the time of application remove ticks already on the cat. The prevention of infestations with new ticks starts within 48 hours after application of the collar. \u0026lt;br\u0026gt;\u003cbr\u003e\nAids in the treatment and control of Sarcoptic mange. \u0026lt;br\u0026gt;\u003cbr\u003e\nSeresto is water-resistant and remains effective following a shampoo treatment or after exposure to rain or sunlight. Under normal conditions  effectiveness lasts for 8 months. In order to maintain an eight-month duration  cats must not be bathed more than once per month. For cats that get bathed once a month or more  the control duration is reduced to 5 months. \u0026lt;br\u0026gt;\u003cbr\u003e\nOccasionally slight itching may be observed in animals that are not used to wearing collars in the first few days after fitting. Ensure that the collar is not fitted too tightly. Slight hair loss and mild skin reactions due to the mechanical irritation of the collar may occur at the application sites which usually recover within 1 or 2 weeks without the need for collar removal. If you notice any serious effects or other effects not mentioned in this leaflet  please inform your veterinarian. \u0026lt;br\u0026gt;\u003cbr\u003e\nIn case of loss of collar  a new collar may be applied immediately. \u0026lt;br\u0026gt;\u003cbr\u003e\nDo not attach a leash to the collar as this may cause breakage.\u0026lt;br\u0026gt; - INGREDIENTS:Flumthrin 4.5%, Imidacloprid 10.0%, Other Ingredients 85.5%, Total 100.0% - MATERIAL\/COMP:Solid (e.g. Chews  Tablet  Toy) - HEIGHT(INCHES): 1.500 - WIDTH(INCHES):4.750 - LENGTH(INCHES):4.750\u003c\/p\u003e","brand":"Elanco","offers":[{"title":"Silver","offer_id":42774916137022,"sku":"E8AF","price":59.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0601\/6686\/4958\/files\/e8af-studio-0.jpg?v=1778769871"}],"url":"https:\/\/www.petscriptdirect.com\/collections\/animal-health-wellness-flea-tick-control.oembed","provider":"PetScript Direct","version":"1.0","type":"link"}